Cisplatin electrolyte abnormalities

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August undefined, 2024

Webmay drive unique electrolyte disorders in different malignancies. In the next sections, the clinical fea-tures, pathophysiology, and treatment of the most … WebSep 18, 2024 · NCBI Bookshelf

Hypomagnesemia (Low Level of Magnesium in the Blood)

WebDec 29, 2024 · Anticancer agents associated with electrolyte abnormalities included cisplatin, carboplatin, oxaliplatin, vincristine, vinblastine, cyclophosphamide and ifosfamide. CKD, chronic kidney disease. Open in new tab Incidence of hyponatremia and other electrolyte abnormalities WebJun 8, 2024 · Acute overdosage with cisplatin injection may result in renal failure, hepatic failure, hearing loss, ocular toxicity, myelosuppression, nausea and vomiting, and neuritis. shrubs for privacy fence

(PDF) Electrolyte disorders with platinum-based chemotherapy ...

WebFeb 16, 2024 · Common side effects of cisplatin may include: hearing problems; kidney problems; numbness or tingling; nausea, vomiting; or. bone marrow suppression. This is … Web5.3 Electrolyte and Metabolic Abnormalities In addition to causing hyperkalemia, spironolactone tablets can cause hyponatremia, hypomagnesemia, hypocalcemia, hypochloremic alkalosis, and hyperglycemia. Asymptomatic hyperuricemia can occur and rarely gout is precipitated. Monitor serum electrolytes, uric acid and blood glucose … WebOct 19, 2024 · In the literature, cisplatin-associated electrolyte abnormalities are poorly described, but hypomagnesemia occurs in 14–94% of children [3, 4, 36, 38, 39]. CNS … theory job opportunities

Cisplatin - LiverTox - NCBI Bookshelf - National Center for ...

Asclemed USA, Inc. SPIRONOLACTONE- spironolactone tablet, …

WebMay 18, 2024 · Amphotericin B is used in the treatment of often life-threatening fungal infections (see "Pharmacology of amphotericin B"). Impaired kidney function is a … Webcisplatin, and was severe in 20%. Monitor patients for hypomagnesemia, hypocalcemia, and hypokalemia prior to each dose of PORTRAZZA during treatment and for at least 8 weeks following completion of PORTRAZZA. Withhold PORTRAZZA for Grade 3 or 4 electrolyte abnormalities. Replete electrolytes as medically appropriate. (5.2) theory jiu jitsuWebJul 20, 2024 · Electrolyte abnormalities that converge on hypomagnesemia and serve as important diagnostic clues to its presence include … shrubs for privacy wall

"WebJul 28, 2024 · Electrolyte Abnormalities: This medication can affect the normal levels of electrolytes (potassium, magnesium, calcium, etc.) in your body. Your levels will be monitored using blood tests. If your levels become too low, your care team may prescribe specific electrolytes to be given by IV or taken by mouth. " - Cisplatin electrolyte abnormalities

Cisplatin electrolyte abnormalities

WebNational Center for Biotechnology Information WebMay 1, 2024 · The most common diagnoses were central nervous system tumors (58 [36%]), neuroblastoma (43 [27%]), and osteosarcoma (33 [21%]). Acute kidney injury (by serum creatinine level increase) occurred in 48 of 159 patients (30%) at early cisplatin infusions and 23 of 143 patients (16%) at late cisplatin infusions.

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WebSep 15, 2024 · Deafness after the initial dose of cisplatin (cisplatin injection) has been reported rarely. Ototoxic effects may be more severe in children receiving cisplatin … WebApr 12, 2024 · In cancer patients, electrolyte disorders are frequent due to tubular functional abnormalities related to chemotherapeutic drugs, the TLS and the impaired secretion of antidiuretic hormone ... As previously described, also the cisplatin can induce electrolyte imbalances. In this case, the standard approach to avoid cisplatin-induced ...

WebNov 1, 2024 · Special attention needs to be paid to electrolyte disturbances, which should be particularly considered when administering high doses of cisplatin [19]. The most common electrolyte disorder is ... WebJun 8, 2024 · Cisplatin injection can cause dose-related peripheral neuropathy that becomes more severe with repeated courses of the drug. Neurologic symptoms have …

WebOct 19, 2024 · Severe electrolyte abnormalities (secondary exposure) included ≥ grade three hypophosphatemia, hypokalemia, or hypomagnesemia (National Cancer Institute Common Terminology Criteria for Adverse Events v4.0). CKD was albuminuria or decreased kidney function for age (KDIGO guidelines).

WebMay 24, 2006 · This drug should be considered among the possible causes of chronic unexplained electrolyte disorders. Cisplatin is a well-known nephrotoxic antineoplastic … shrubs for privacy screeningWebApr 15, 2016 · 3. Platinum-containing drugs (cisplatin, carboplatin and oxaliplatin) Cisplatin, carboplatin and oxaliplatin are platinum-containing anticancer drugs targeting solid cancers, such as head and neck cancer, lung cancer, and cervical cancer (Ali et al., 2013).The use of these drugs has been associated with a number of electrolyte … theory job satisfactionWebSep 15, 2024 · Cisplatin is administered parenterally and is available in 50 and 100 mg vials in generic forms and under the brand name Platinol. The recommended dose varies by indication, tumor type, patient age and body weight. Common side effects include nausea, vomiting, bone marrow suppression, electrolyte imbalance, neuropathy, ototoxicity and ... shrubs for privacy ukWebJun 10, 2024 · However, cisplatin is known to cause a variety of adverse effects (such as nausea and vomiting, renal insufficiency, electrolyte abnormalities, myelosuppression, ototoxicity, peripheral neuropathy, hepatotoxicity, and retinopathy) than other chemotherapy regimens. Diarrhea, pancreatitis, seizures, and respiratory failure have also been reported. shrubs for rockery ukWebJan 3, 2024 · A variety of kidney diseases and electrolyte disorders can result from the drugs that are used to treat malignant disease, including conventional cytotoxic agents; molecularly targeted agents, which take advantage of molecular abnormalities that drive cancer progression; and immunotherapeutic agents. shrubs for privacy zone 6bWebCisplatin is a coordinate metal complex with significant antineoplastic activity and various effects, including acute anc chronic renal insufficiency and renal magnesium … theory jogger pant in tech stretch knitWebCisplatin is widely used in the treatment of multiple cancers, including metastatic gonadal tumors and advanced bladder cancer. ... Some cases of ventricular fibrillation have occurred in the setting of documented electrolyte abnormalities that can develop right after amsacrine administration. 85 The importance of maintaining electrolyte ... shrubs for privacy screen