On the nature of seizure dynamics

Web4 de mai. de 2024 · Author summary Much attention has been devoted to the mechanisms underlying epileptic seizures. However, so far, the morphology of how seizures start on electrographic recordings (i.e. the seizure onset pattern) has been neglected as a potential indicator of the underlying dynamic mechanism. In this work, we take a spatio-temporal … Web18 de dez. de 2024 · Furthermore, this approach distinguished brain regions with seizures from seizure-free brain regions in the epileptic rat strain. We suggest that fast oxygen dynamics may be a useful biomarker for ...

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Web13 de jun. de 2014 · Here, we analysed seizure dynamics mathematically and established a taxonomy of seizures based on first principles. For the predominant seizure class we … Webdynamics involving pyramidal cells and local interneurons, high- lighting the increases in excitability and decreases in slow dendri- tic and fast synaptic inhibition that peak at … fitness first fee philippines https://lostinshowbiz.com

On the modelling of seizure dynamics - PMC - National Center for ...

Web11 de ago. de 2024 · Optimizing antiepileptic drug therapy is very challenging due to the absence of a reliable method to assess how brain activity changes between seizures. This work uses the Taxonomy of Seizure... Web21 de jul. de 2014 · A formal understanding of how seizure dynamics are generated could therefore provide vital constraints on dynamic causal models of seizure activity. In … Web27 de mar. de 2024 · This study presents a novel method that characterizes the dynamic behavior of pediatric seizure events and introduces a systematic approach to locate the nullclines on the phase space when the governing differential equations are unknown. can i bring a pillow pet on a plane

Carbamazepine and GABA have distinct effects on seizure onset dynamics …

Category:Patient-Specific Seizure Detection Using Nonlinear Dynamics and ...

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On the nature of seizure dynamics

Mechanisms underlying different onset patterns of focal seizures

Web14 de out. de 2024 · According to an existing classification, two basic types of dynamic onset patterns plus a number of more complex onset waveforms can be distinguished. Here, we introduce a basic three-variable model with two time scales to study potential mechanisms of spontaneous seizure onset. Web26 de nov. de 2024 · The mechanism of seizure emergence and the role of brief interictal epileptiform discharges (IEDs) in seizure generation are two of the most important …

On the nature of seizure dynamics

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Web15 de mar. de 2024 · The average periodicity varies individually, but group trends (multidien seizure chronotypes) 58 include about-monthly periodicity of ~20–35 days 51 and more … Web7 de fev. de 2024 · Our study sheds new light on the nature of phase transitions and fluctuations in seizure spreading dynamics. We expect it to play an important role in the development of closed-loop stimulation approaches for preventing seizure spread in pharmacologically resistant epilepsy.

Webscientific article Web7 de out. de 2024 · The basic dynamic mechanism that underlies the occurrence of these abnormal electrical patterns in the brain is not well understood. The current paper aims …

WebSeizures can occur spontaneously and in a recurrent manner, which defines epilepsy; or they can be induced in a normal brain under a variety of conditions in most … Web14 de mar. de 2024 · The Epileptor field model reproduces multiscale features of spatiotemporal seizure dynamics. a Schematics for the Epileptor field model. At each …

Web22 de fev. de 2024 · Modelling the interactions that arise from neural dynamics in seizure genesis is challenging but important in the effort to improve the success of epilepsy surgery. Dynamical network models ...

WebHere, we analysed seizure dynamics mathematically and established a taxonomy of seizures based on first principles. For the predominant seizure class we developed a generic model called Epileptor. As an experimental model system, we used ictal-like … can i bring a pillow on frontier airlinesWeb1 de jan. de 2024 · However, in realistic conditions seizures spontaneously terminate within a few minutes. This can be explained by taking into account dynamics of other ion concentrations. Intracellular sodium ([Na +] i) progressively increases during a seizure episode due to spiking activity and the slow nature of Na + removal processes (Fig. 1b). fitness first frankfurt am mainWeb14 de ago. de 2014 · Relating the model dynamics to experimental and clinical findings leads us to propose three classes of dynamical mechanisms for the onset of focal seizures in a unified framework. These three classes are: (i) globally induced focal seizures; (ii) globally supported focal seizures; (iii) locally induced focal seizures. can i bring a pocket knife on planeWeb11 de jun. de 2014 · Europe PMC is an archive of life sciences journal literature. fitness first frankfurt welleWeb19 de jan. de 2024 · Seizure suppression. To study the effect of the strength of the backwards connections (connections to the pathological column) on seizure suppression, we studied the dynamics of column 1 while varying backwards connections K i1 (i = 2,…,7). All connectivity constants K i1 were changed simultaneously. fitness first fitness freitagWeb19 de out. de 2024 · Several models are developed to describe the dynamics of seizure generation and termination 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41. These models … fitness first flinders st platinumWeb1 de ago. de 2014 · And somewhat surprisingly, the vast majority of seizure onset-and offset patterns as observed on the EEG can be classified as corresponding to a set of these mathematical forms -highlighting some... can i bring a pregnancy test on a plane